A total protein and A/G ratio blood test is a laboratory test that measures the total amount of protein in the blood and the ratio of two types of protein called albumin and globulin. Albumin is a protein produced by the liver that helps to maintain the balance of fluids in the body, while globulin is a protein produced by the immune system that helps to fight infection and disease. The A/G ratio is calculated by dividing the concentration of albumin in the blood by the concentration of globulin.

The total protein and A/G ratio test is typically ordered to help evaluate overall health and to diagnose and monitor conditions such as liver disease, kidney disease, and malnutrition. The test is performed on a blood sample taken from a vein in the arm.